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Nucleic acid-loaded LNPs

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Lipid Nanoparticles (LNP) are innovative delivery systems that contain RNA or DNA molecules combined with lipids to enable precise and effective delivery of genetic material to target cells and tissues. LNPs have garnered significant attention in the scientific and medical communities as a prominent technology platform that enables the delivery of nucleic acids to prevent and treat various diseases. LNP formulation technology allowed the rapid development of the COVID-19 vaccines, and now many more LNP formulations are in clinical trials for the treatment of infectious diseases, cancer, and genetic disorders.

LNPs are versatile nucleic acid carriers and can encapsulate diverse cargos, including messenger RNA (mRNA), small interference RNA (siRNA), microRNA (miRNA), circular RNA (circRNA), guide RNA ( gRNA), plasmid DNA (pDNA) and antisense oligomers (ASO’s). Their versatility provides a large variety of application options for both preclinical research and translation to the clinic.

At LIPOSOMA we are dedicated to empowering researchers with LNP technology solutions tailored for in vivo, in vitro and in situ applications. With our scientific expertise, we can help you in advancing your research and realizing your medical aims, whether vaccine development or other medical applications.

The manufacturing process of nucleic acid containing LNPs involves several critical steps. The formulation parameters, including lipid composition, lipid-to-nucleic acid ratio, and buffer conditions, will be carefully optimized to achieve the desired particle size and distribution, encapsulation efficiency and stability.

At LIPOSOMA, we understand the special needs and demands of academic and industrial researchers. We provide comprehensive support throughout your research journey, from initial consultation and formulation development to scalable manufacturing and quality control. Our collaborative approach ensures that our nucleic acid LNP solutions align perfectly with your experimental needs, enabling you to achieve consistent and reproducible results.


Would you like to learn more?
Give us a call at 0031 20 237 36 00